LTBP3 Back

latent transforming growth factor beta binding protein 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of LTBP3
The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.

Community Annotation of LTBP3 Add / Edit LTBP3: Annotations

No community annotations yet for LTBP3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LTBP3 is highly significantly mutated in
(none)
LTBP3 is significantly mutated in
(none)
LTBP3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LTBP3