LSP1 Back

lymphocyte-specific protein 1

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NCBI Description of LSP1

This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.

Community Annotation of LSP1 Add / Edit LSP1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LSP1 is highly significantly mutated in
LSP1 is significantly mutated in
LSP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for LSP1