LSM6 Back

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

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NCBI Description of LSM6

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004].

Community Annotation of LSM6 Add / Edit LSM6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LSM6 is highly significantly mutated in
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LSM6 is significantly mutated in
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LSM6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LSM6