LSM4 Back

LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)

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NCBI Description of LSM4

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of LSM4 Add / Edit LSM4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LSM4 is highly significantly mutated in
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LSM4 is significantly mutated in
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LSM4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LSM4