LRRC8E Back

leucine rich repeat containing 8 family, member E

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NCBI Description of LRRC8E
This gene encodes a member of a small, conserved family of proteins with similar structure, including a string of extracellular leucine-rich repeats. A related protein was shown to be involved in B-cell development. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of LRRC8E Add / Edit LRRC8E: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LRRC8E is highly significantly mutated in
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LRRC8E is significantly mutated in
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LRRC8E is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LRRC8E