NCBI Description of LRPPRC
|This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.|
Community Annotation of LRPPRC Add / Edit LRPPRC: Annotations
No community annotations yet for LRPPRC.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.