lysophosphatidylcholine acyltransferase 4

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NCBI Description of LPCAT4

Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).[supplied by OMIM, May 2008].

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LPCAT4 is highly significantly mutated in
LPCAT4 is significantly mutated in
LPCAT4 is near significance in

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Data details

Mutation list for LPCAT4