LPCAT4 Back

lysophosphatidylcholine acyltransferase 4

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NCBI Description of LPCAT4
Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).[supplied by OMIM, May 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LPCAT4 is highly significantly mutated in
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LPCAT4 is significantly mutated in
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LPCAT4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LPCAT4