LPAR2 Back

lysophosphatidic acid receptor 2

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NCBI Description of LPAR2

This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined.

Community Annotation of LPAR2 Add / Edit LPAR2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LPAR2 is highly significantly mutated in
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LPAR2 is significantly mutated in
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LPAR2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LPAR2