LMO3 Back

LIM domain only 3 (rhombotin-like 2)

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NCBI Description of LMO3

The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene.

Community Annotation of LMO3 Add / Edit LMO3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LMO3 is highly significantly mutated in
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LMO3 is significantly mutated in
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LMO3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LMO3