LLGL1 Back

lethal giant larvae homolog 1 (Drosophila)

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NCBI Description of LLGL1
This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Community Annotation of LLGL1 Add / Edit LLGL1: Annotations

No community annotations yet for LLGL1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LLGL1 is highly significantly mutated in
(none)
LLGL1 is significantly mutated in
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LLGL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LLGL1