lipase, family member N

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of LIPN

The gene encodes a lipase that is highly expressed in granular keratinocytes in the epidermis, and plays a role in the differentiation of keratinocytes. Mutations in this gene are associated with lamellar ichthyosis type 4.

Community Annotation of LIPN Add / Edit LIPN: Annotations

No community annotations yet for LIPN.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LIPN is highly significantly mutated in
LIPN is significantly mutated in
LIPN is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for LIPN