LIPN Back

lipase, family member N

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NCBI Description of LIPN
The gene encodes a lipase that is highly expressed in granular keratinocytes in the epidermis, and plays a role in the differentiation of keratinocytes. Mutations in this gene are associated with lamellar ichthyosis type 4.

Community Annotation of LIPN Add / Edit LIPN: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LIPN is highly significantly mutated in
(none)
LIPN is significantly mutated in
(none)
LIPN is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LIPN