LIPI Back

lipase, member I

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NCBI Description of LIPI

The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. The encoded protein, which can be inhibited by sodium vanadate, may be found exclusively in sperm. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia.

Community Annotation of LIPI Add / Edit LIPI: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LIPI is highly significantly mutated in
(none)
LIPI is significantly mutated in
(none)
LIPI is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LIPI