LIM2 Back

lens intrinsic membrane protein 2, 19kDa

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of LIM2
This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of LIM2 Add / Edit LIM2: Annotations

No community annotations yet for LIM2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LIM2 is highly significantly mutated in
(none)
LIM2 is significantly mutated in
(none)
LIM2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LIM2