LILRA4 Back

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4

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NCBI Description of LILRA4

This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte receptor gene cluster (LRC) at chromosomal region 19q13.4.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LILRA4 is highly significantly mutated in
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LILRA4 is significantly mutated in
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LILRA4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LILRA4