LHX9 Back

LIM homeobox 9

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NCBI Description of LHX9
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants.

Community Annotation of LHX9 Add / Edit LHX9: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LHX9 is highly significantly mutated in
(none)
LHX9 is significantly mutated in
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LHX9 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LHX9