LHX6 Back

LIM homeobox 6

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NCBI Description of LHX6

This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Community Annotation of LHX6 Add / Edit LHX6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LHX6 is highly significantly mutated in
(none)
LHX6 is significantly mutated in
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LHX6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LHX6