LHX2 Back

LIM homeobox 2

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NCBI Description of LHX2

This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.

Community Annotation of LHX2 Add / Edit LHX2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LHX2 is highly significantly mutated in
LHX2 is significantly mutated in
LHX2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for LHX2