LGR6 Back

leucine-rich repeat-containing G protein-coupled receptor 6

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NCBI Description of LGR6
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants.

Community Annotation of LGR6 Add / Edit LGR6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LGR6 is highly significantly mutated in
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LGR6 is significantly mutated in
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LGR6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LGR6