LGALS9 Back

lectin, galactoside-binding, soluble, 9 (galectin 9)

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NCBI Description of LGALS9

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.

Community Annotation of LGALS9 Add / Edit LGALS9: Annotations

No community annotations yet for LGALS9.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LGALS9 is highly significantly mutated in
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LGALS9 is significantly mutated in
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LGALS9 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LGALS9