LGALS8 Back

lectin, galactoside-binding, soluble, 8 (galectin 8)

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NCBI Description of LGALS8
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of LGALS8 Add / Edit LGALS8: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LGALS8 is highly significantly mutated in
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LGALS8 is significantly mutated in
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LGALS8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LGALS8