LEPROT Back

leptin receptor overlapping transcript

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NCBI Description of LEPROT
LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010].

Community Annotation of LEPROT Add / Edit LEPROT: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LEPROT is highly significantly mutated in
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LEPROT is significantly mutated in
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LEPROT is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LEPROT