LEO1 Back

Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

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NCBI Description of LEO1
LEO1, parafibromin (CDC73; MIM 607393), CTR9 (MIM 609366), and PAF1 (MIM 610506) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]).[supplied by OMIM, Mar 2008].

Community Annotation of LEO1 Add / Edit LEO1: Annotations

No community annotations yet for LEO1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LEO1 is highly significantly mutated in
(none)
LEO1 is significantly mutated in
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LEO1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LEO1