ligand dependent nuclear receptor corepressor

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NCBI Description of LCOR

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008].

Community Annotation of LCOR Add / Edit LCOR: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LCOR is highly significantly mutated in
LCOR is significantly mutated in
LCOR is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for LCOR