LCMT2 Back

leucine carboxyl methyltransferase 2

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NCBI Description of LCMT2
The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW).

Community Annotation of LCMT2 Add / Edit LCMT2: Annotations

No community annotations yet for LCMT2.
Sort mutations by: Tumor type  Mutation type  Position  
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LCMT2 is highly significantly mutated in
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LCMT2 is significantly mutated in
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LCMT2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LCMT2