LARP7 Back

La ribonucleoprotein domain family, member 7

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NCBI Description of LARP7
This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants.

Community Annotation of LARP7 Add / Edit LARP7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LARP7 is highly significantly mutated in
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LARP7 is significantly mutated in
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LARP7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LARP7