lysosomal-associated protein transmembrane 4 alpha

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NCBI Description of LAPTM4A

This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined; however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LAPTM4A is highly significantly mutated in
LAPTM4A is significantly mutated in
LAPTM4A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for LAPTM4A