LanC lantibiotic synthetase component C-like 1 (bacterial)

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NCBI Description of LANCL1

This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Community Annotation of LANCL1 Add / Edit LANCL1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


LANCL1 is highly significantly mutated in
LANCL1 is significantly mutated in
LANCL1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for LANCL1