LAMP3 Back

lysosomal-associated membrane protein 3

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NCBI Description of LAMP3

Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

Community Annotation of LAMP3 Add / Edit LAMP3: Annotations

No community annotations yet for LAMP3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LAMP3 is highly significantly mutated in
(none)
LAMP3 is significantly mutated in
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LAMP3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LAMP3