LAMP2 Back

lysosomal-associated membrane protein 2

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NCBI Description of LAMP2

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.

Community Annotation of LAMP2 Add / Edit LAMP2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LAMP2 is highly significantly mutated in
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LAMP2 is significantly mutated in
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LAMP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for LAMP2