LAG3 Back

lymphocyte-activation gene 3

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NCBI Description of LAG3
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by published experimental evidence.

Community Annotation of LAG3 Add / Edit LAG3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

LAG3 is highly significantly mutated in
(none)
LAG3 is significantly mutated in
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LAG3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for LAG3