KTN1 Back

kinectin 1 (kinesin receptor)

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NCBI Description of KTN1

This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KTN1 is highly significantly mutated in
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KTN1 is significantly mutated in
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KTN1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KTN1