KRTAP4-11 Back

keratin associated protein 4-11

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NCBI Description of KRTAP4-11
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Community Annotation of KRTAP4-11 Add / Edit KRTAP4-11: Annotations

No community annotations yet for KRTAP4-11.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KRTAP4-11 is highly significantly mutated in
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KRTAP4-11 is significantly mutated in
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KRTAP4-11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KRTAP4-11