KRTAP1-5 Back

keratin associated protein 1-5

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NCBI Description of KRTAP1-5

This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21.

Community Annotation of KRTAP1-5 Add / Edit KRTAP1-5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KRTAP1-5 is highly significantly mutated in
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KRTAP1-5 is significantly mutated in
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KRTAP1-5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KRTAP1-5