KRT28 Back

keratin 28

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NCBI Description of KRT28
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. Sequence Note: This RefSeq contains an in-frame start site 22 codons upstream from the currently annotated site but is not being annotated as a start site since it is in a weak Kozak sequence context and no support was found for use of the upstream AUG.

Community Annotation of KRT28 Add / Edit KRT28: Annotations

No community annotations yet for KRT28.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KRT28 is highly significantly mutated in
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KRT28 is significantly mutated in
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KRT28 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KRT28