KRT18 Back

keratin 18

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NCBI Description of KRT18

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Community Annotation of KRT18 Add / Edit KRT18: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


KRT18 is highly significantly mutated in
KRT18 is significantly mutated in
KRT18 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for KRT18