KNTC1 Back

kinetochore associated 1

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NCBI Description of KNTC1

This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Community Annotation of KNTC1 Add / Edit KNTC1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


KNTC1 is highly significantly mutated in
KNTC1 is significantly mutated in
KNTC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for KNTC1