KLRF1 Back

killer cell lectin-like receptor subfamily F, member 1

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NCBI Description of KLRF1

KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009].

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


KLRF1 is highly significantly mutated in
KLRF1 is significantly mutated in
KLRF1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for KLRF1