KLRF1 Back

killer cell lectin-like receptor subfamily F, member 1

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NCBI Description of KLRF1
KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KLRF1 is highly significantly mutated in
(none)
KLRF1 is significantly mutated in
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KLRF1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KLRF1