KLK12 Back

kallikrein-related peptidase 12

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NCBI Description of KLK12
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms.

Community Annotation of KLK12 Add / Edit KLK12: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KLK12 is highly significantly mutated in
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KLK12 is significantly mutated in
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KLK12 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KLK12