KLK11 Back

kallikrein-related peptidase 11

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of KLK11
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.

Community Annotation of KLK11 Add / Edit KLK11: Annotations

No community annotations yet for KLK11.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KLK11 is highly significantly mutated in
(none)
KLK11 is significantly mutated in
(none)
KLK11 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KLK11