KLHL4 Back

kelch-like 4 (Drosophila)

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NCBI Description of KLHL4

This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Community Annotation of KLHL4 Add / Edit KLHL4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KLHL4 is highly significantly mutated in
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KLHL4 is significantly mutated in
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KLHL4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KLHL4