KLHL17 Back

kelch-like 17 (Drosophila)

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NCBI Description of KLHL17

The protein encoded by this gene is expressed in neurons of most regions of the brain. It contains an N-terminal BTB domain, which mediates dimerization of the protein, and a C-terminal Kelch domain, which mediates binding to F-actin. This protein may play a key role in the regulation of actin-based neuronal function.

Community Annotation of KLHL17 Add / Edit KLHL17: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KLHL17 is highly significantly mutated in
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KLHL17 is significantly mutated in
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KLHL17 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KLHL17