kelch domain containing 8B

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NCBI Description of KLHDC8B

This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Mutations in this gene have been associated with Hodgkin lymphoma.

Community Annotation of KLHDC8B Add / Edit KLHDC8B: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


KLHDC8B is highly significantly mutated in
KLHDC8B is significantly mutated in
KLHDC8B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for KLHDC8B