KLHDC8A Back

kelch domain containing 8A

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NCBI Description of KLHDC8A
This gene encodes a kelch domain-containing protein which is upregulated in cancer. Upregulated expression of the encoded protein may provide an alternative pathway for tumors to maintain aggressiveness in the absence of epidermal growth factor receptor dependence. Alternative splicing results in multiple transcript variants.

Community Annotation of KLHDC8A Add / Edit KLHDC8A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KLHDC8A is highly significantly mutated in
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KLHDC8A is significantly mutated in
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KLHDC8A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KLHDC8A