KLHDC3 Back

kelch domain containing 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of KLHDC3
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination.

Community Annotation of KLHDC3 Add / Edit KLHDC3: Annotations

No community annotations yet for KLHDC3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KLHDC3 is highly significantly mutated in
(none)
KLHDC3 is significantly mutated in
(none)
KLHDC3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KLHDC3