KISS1R Back

KISS1 receptor

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of KISS1R
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.

Community Annotation of KISS1R Add / Edit KISS1R: Annotations

No community annotations yet for KISS1R.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KISS1R is highly significantly mutated in
(none)
KISS1R is significantly mutated in
(none)
KISS1R is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KISS1R