KIF22 Back

kinesin family member 22

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NCBI Description of KIF22
The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of KIF22 Add / Edit KIF22: Annotations

No community annotations yet for KIF22.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KIF22 is highly significantly mutated in
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KIF22 is significantly mutated in
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KIF22 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KIF22