KIF21A Back

kinesin family member 21A

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NCBI Description of KIF21A
This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.

Community Annotation of KIF21A Add / Edit KIF21A: Annotations

No community annotations yet for KIF21A.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KIF21A is highly significantly mutated in
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KIF21A is significantly mutated in
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KIF21A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KIF21A