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KIAA1549

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NCBI Description of KIAA1549

The protein encoded by this gene belongs to the UPF0606 family. This gene has been found to be fused to the BRAF oncogene in many cases of pilocytic astrocytoma. The fusion results from 2Mb tandem duplications at 7q34. Alternative splicing results in multiple transcript variants.

Community Annotation of KIAA1549 Add / Edit KIAA1549: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KIAA1549 is highly significantly mutated in
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KIAA1549 is significantly mutated in
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KIAA1549 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for KIAA1549