KIAA1109 Back


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NCBI Description of KIAA1109

This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development.

Community Annotation of KIAA1109 Add / Edit KIAA1109: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


KIAA1109 is highly significantly mutated in
KIAA1109 is significantly mutated in
KIAA1109 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for KIAA1109