KIAA0319 Back

KIAA0319

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NCBI Description of KIAA0319
This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of KIAA0319 Add / Edit KIAA0319: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

KIAA0319 is highly significantly mutated in
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KIAA0319 is significantly mutated in
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KIAA0319 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for KIAA0319